Owners have filed 36 complaints with NHTSA about this car, most about the electrical, engine, and transmission. The 9 checks below target those problems, in the order you would do them at the car.
2021Tick items off on your phone at the car, or print it. Ticks stay on this device.
0/9 checked
2021 Mercedes-Benz E-Class: inspection sheet
Before you go, or before you touch the car0/4
Ask the seller not to warm the car up first0/2
At least 20 minutes, with some highway0/3
These checks are specific to this model year. For tires, body panels, fluids, and the other basics every used car needs, use the general inspection guide.
These years share the 2021's design and most of its parts, so their problems are the ones to look for on this car too.
Worth adding to your 2021 checks
Worth adding to your 2021 checks
Worth adding to your 2021 checks
Owners report these failures starting around the mileages below. A car inside one of these ranges deserves a closer look at that part, or records showing it was already fixed.
48-volt battery failure
196–3,400 miles
Transmission failure
15,000–22,000 miles
NHTSA complaints for the 2021 Mercedes-Benz E-Class, grouped by the part owners named. Open a row to read what goes wrong.
The 48-volt battery dies early and leaves the car unable to start or move, sometimes before 1,000 miles. Cars get towed for a battery replacement, and one owner waits more than three weeks for the part. Warnings that the 12-volt battery is low show up along with camera dropouts and an accelerator that does not respond. In the one fire-related report, the car smokes and catches fire at idle after a 12 Volt Battery message. Other reports cite misfires, power loss at a light, and an overheating warning that slows the car below 20 mph.
Cylinder misfires turn on the check engine light and put the car in limp mode, which cuts power, even on the freeway. A dealer traces one case to a leaking exhaust valve on cylinder 4, tied to a service bulletin on valve seat wear in M260 engines. Mercedes denies warranty coverage, and one repair estimate is over $7,600. The 48-volt mild hybrid battery also fails within weeks of delivery. The car will not start and needs a flatbed tow, with repeat replacements at 196 and 735 miles.
The transmission fails completely at low mileage, at about 15,000 and 22,000 miles in these reports. One failure happens at highway speed. The driver gets off the highway, but the car cannot move afterward and the owner is stranded. Neither report describes warning signs before the failure, a dealer diagnosis, or how the repair turned out. With only 2 complaints, the pattern is thin, but both describe a total loss of the transmission rather than a minor drivability quirk.
The rearview camera and 360 view do not appear in reverse, often with a system inoperative message, and the parking sensors can drop out at the same time. Restarting the car does not always bring the image back. The fault comes and goes and gets more frequent over 2 years, which makes it hard to show a dealer. Losing the camera and sensors reduces awareness of what is behind the car and raises crash risk when backing up. Owners connect the problem to recall campaign 21V228000.
Excerpts from complaints E-Class owners filed with NHTSA, as written. Listen for the same symptoms on your test drive.
48Volt battery failed after three months and just 3,400 miles. I understand this is a recurring problem with Mercedes. Car had to be towed as the vehicle was totally inoperable due to battery malfunction. It took more than three weeks for Mercedes to provide a replacement battery. From what I have read, there is a strong likelihood that the battery will fail again.
Filed with NHTSA, August 2021
FIRE FIRE FIRE Information light came on just saying 12 Volt Battery. I sat in the car letting it idle for about 3 minutes. It began to smoke and then burst into flames. I called 911 got the fire department here but by the time they were here there was not much left. The car essentially burned to the ground and insurance has declared it a total loss. Car was in my driveway, was certainly a danger to me, to my house and to my neighbor's cars and house.
Filed with NHTSA, December 2024
Engine keeps having a misfire that Mercedes put a TSB out for and once the misfire happen I cause the vehicle to go in a limp mode which causes the vehicle to loose power happened to me in the freeway. The car had 54K miles and Mercedes refused to repair the issue as the engine part failure isn’t common.
Filed with NHTSA, December 2025
The Mercedes E350, with 22,000 miles suffered a catastrophic transmission failure while driving on the highway. I managed to exit the highway but the car could not be moved and left me stranded.
Filed with NHTSA, July 2025
With the car only have about 15,000 miles the transmission has failed . I have seen there have been recalls of other models with similar complaints of transmission failure .
Filed with NHTSA, January 2026
I was parking and the 360 view sensor did not come up. When I tried to back out and move forward again, I realized the back up camera would not come on. I turned the car on and off and then tried again to reverse to engage the camera but was instead given a message that says system inoperative.
Filed with NHTSA, May 2024
Complaints for this year next to the average for the other model years, area by area.
The 2021 ranks third for owner complaints among 7 E-Class years, well under the average of the others. Newer years have had less time to collect complaints, so compare like with like.
Redesigns and mid-cycle updates change what can go wrong.
The 2021 is the sixth model year of the E-Class's fifth generation (2016–2023).
It includes the 2020 update.
What changed for 2020
Recall repairs are free at any Mercedes-Benz dealer, but the seller may never have had them done. Check each campaign number against the VIN.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 CLS450, E450, E450 All-Terrain, AMG E53, AMG GT43, AMG GT53, and 2021 AMG CLS53 vehicles. The 48-volt ground cable connection located in the engine compartment may not be tightened properly and may result in the ground cable overheating.
Risk: An overheated ground cable increases the risk of a fire.
Fix: Dealers will inspect the 48-volt ground cable connection and repair it as necessary, free of charge. Owner notification letters were mailed March 22, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024MMNNNN.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
Risk: A loss of drive power can increase the risk of a crash.
Fix: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2022 CLS450 Coupe and AMG E53, 2019-2021 AMG CLS53 Coupe, and 2021-2022 E450 vehicles. The 12-Volt battery in the trunk may not be properly secured, which, in the event of a crash, can cause electrical connection failure, disabling various safety features including, emergency call (eCall) system, electric seat adjustment, hazard warning lights, and automatic door locks.
Risk: The inability to operate safety features (eCall system, hazard lights, electric seats, or automatic door locks) can increase the risk of injury during a crash.
Fix: Dealers will secure the 12V battery, free of charge. Owner notification letters were mailed January 20, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022100009.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.
Risk: A disabled eCall system would prevent a vehicle occupant from contacting the emergency services call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.
Fix: The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's numbers are for this recall is 2022060005 and 2023110006.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2018-2021 CLA-Class, GLE/GLS-Class, A-Class, C-Class, E-Class, E-Class Coupe/Convertible, GLA/GLB-Class, GLC-Class, and CLS-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The rearview camera may not display the rearview image due to a software error. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 111, "Rear Visibility.".
Risk: An inoperable rearview camera display reduces the driver's rear view, increasing the risk of a crash.
Fix: Dealers will update the rearview camera software, free of charge. Owner notification letters were mailed July 15, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022060007.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.
Risk: Deactivated hands-off detection will prevent DISTRONIC system features from functioning, including warnings to grab the steering wheel and calling first responders as part of the Active Emergency Stop Assist, which can increase the risk of a crash or injury.
Fix: Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040010.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 CLS450, AMG E53, AMG CLS53, E350, E450, AMG GT43, AMG GT53, 2020 S450, S560, G550, AMG GLC63, 2020-2021 GLC300, and AMG G63 vehicles. The side crash sensor connectors may come loose, which could delay the activation of air bags and seatbelts during a side impact crash.
Risk: Air bags and seatbelts that don't function as intended can increase the risk of injury during a crash.
Fix: Dealers will inspect and replace as necessary, the side impact crash sensors, free of charge. Owner notification letters were mailed on September 3, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021070032/33.
Mercedes-Benz, LLC (MBUSA) is recalling certain 2021 G550, AMG G63, E350, E450, AMG CLS53, AMG E53, AMG GT43, AMG GT53, AMG GT63, 2021-2022 CLS450, and AMG E63 vehicles. The rear seat belt automatic locking retractors may deactivate early, which can prevent the child restraint system from securing properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 208, "Occupant Crash Protection.".
Risk: An unsecured child restraint system can increase the risk of injury during a crash.
Fix: Dealers will inspect, and replace as necessary, the rear seat belt assemblies, free of charge. Owners notified of the voluntary recall campaign by an interim letter on August 13, 2021. A final letter was mailed on September 24, 2021. Owners may contact MBUSA customer service at 1-800-367-6372.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 C300 Cabriolet, C43 AMG Cabriolet, C63 AMG Cabriolet, C63 AMG S Cabriolet, E450 Cabriolet, and E53 AMG Cabriolet vehicles. The rear headrests may be incorrectly mounted to the seatbacks.
Risk: Incorrectly mounted headrests could move or detach from the seat during a crash, increasing the risk of injury.
Fix: Dealers will inspect the rear seatback guide bushings and replace them if necessary, free of charge. Owner notification letters were mailed July 16, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021060010.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The MBUX multimedia system software may cause the display to remain black, or reboot after startup. This could result in the rearview camera image not displaying properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) number 111, "Rear Visibility.".
Risk: A backup camera that displays a blank image reduces the driver's rear view, increasing the risk of a crash or injury.
Fix: The multimedia system software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed beginning June 28, 2021. Owners may contact MBUSA customer service at 1-800-367-6373. MBUSA's number for this recall is 2021050012.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, and AMG E63 vehicles. The parking control unit may fail to display the rearview camera image and cause the parking sensors to misidentify or fail to detect objects.
Risk: An inoperative rearview camera display and/or parking sensors can reduce the driver's view and awareness of what is behind the vehicle, increasing the risk of a crash.
Fix: All affected vehicles are still within MBUSA's control. MBUSA will replace the parking control unit, free of charge. The recall began April 8, 2021. Owner may contact MBUSA customer service at 1-800-367-6372.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 C-Class, E-Class, E-Class Coupe and Convertible, GLC, CLS, AMG GT 4-door Coupe and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. A faulty electrical contact within the seat position switch may prevent the driver and passenger air bags and seat belt force limiters from properly activating during a crash.
Risk: Air bags and seat belts that do not perform properly in a crash can increase the risk of injury.
Fix: MBUSA will notify owners, and dealers will replace the seat position switches, free of charge. Owner letters were mailed May 21, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021040016.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, E63S AMG, 2020 E63S AMG Wagon, and 2020-2021 E53 AMG vehicles. The passenger seat limiter may allow the seat to be positioned too close to the air bag.
Risk: A seat too close to the air bag increases the risk of injury in the event of a crash necessitating the deployment of the frontal passenger air bag.
Fix: MBUSA will notify owners, and dealers will recalibrate the passenger seat limiter, free of charge. The recall began April 29, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021040002.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles. Please refer to the Part 573 report for specific vehicle model details. The software design of the communication module may fail to communicate the correct vehicle location for the emergency call system (eCall) in the event of a crash.
Risk: Failure of the eCall system may result in emergency responders being dispatched to the wrong location, increasing the risk of injury following a crash.
Fix: MBUSA will notify owners, and the communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. The recall began March 12, 2021. Owners may contact MBUSA customer service at 1-877-762-8267. MBUSA's number for this recall is 2021020025.
Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2021 E350 and E450, 2019-2021 AMG E53 and 2020-2021 AMG E63 vehicles. The front passenger seat may be missing the mechanical seat adjustment range limit stop, allowing the seat to move outside of the acceptable range in relation to the air bag.
Risk: If the front passenger seat is adjusted beyond the acceptable range in relation to the air bag, there could be an increased risk of injury in the event of a crash with air bag deployment.
Fix: MBUSA will notify owners, and dealers will inspect for the mechanical seat adjustment range limitation for the front passenger seat and install it if necessary, free of charge. The recall began December 18, 2020. Owners may contact MBUSA customer service at 1-800-368-6372. MBUSA's number for this recall is 2020110013.
Cars shoppers compare with the Mercedes-Benz E-Class, with their own 2021 checklists.
2021 owner complaints, side by side
